Description

Phenol, 2-Chloro-4,6-Difluoro- is a halogenated phenol derivative characterized by its unique substitution pattern, serving as a versatile and critical building block in advanced organic synthesis. This compound is valued for its ability to introduce both chloro and difluoro functional groups into target molecules, enabling precise modulation of electronic and steric properties. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic cores.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides, where the difluoro and chloro groups enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Used in the production of advanced electronic display materials and organic light-emitting diodes (OLEDs) due to its ability to fine-tune molecular polarity and conjugation.
• Polymer Modification: Serves as a monomer or additive for creating specialty polymers with enhanced flame retardancy, chemical resistance, or specific optical properties.
• Chemical Research & Development: Essential reagent in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound libraries.
• Dye & Pigment Intermediate: Used in the synthesis of complex dyes and high-performance pigments.

Basic Information

Product Name	Phenol, 2-Chloro-4,6-Difluoro-
CAS No.	2267-99-4
Molecular Formula	C6H3ClF2O
Molecular Weight	164.54 g/mol
Synonyms	2-Chloro-4,6-difluorophenol; 4,6-Difluoro-2-chlorophenol; 2-Chloro-4,6-difluoro-1-hydroxybenzene; 1-Chloro-3,5-difluoro-2-hydroxybenzene; Phenol, 2-chloro-4,6-difluoro-; 2267-99-4; 2-Cl-4,6-F2-Phenol
EINECS	Contact for details

Quality Control

Our Phenol, 2-Chloro-4,6-Difluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.