Description

Sodium Pentafluorophenoxide is the sodium salt of pentafluorophenol, a versatile and highly reactive chemical intermediate. Its value lies in its role as a superior leaving group in nucleophilic substitution reactions, enabling efficient synthesis in complex organic chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for active ingredient development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorination enhances biological activity and stability.
• Peptide Coupling Agent: Acts as an activating agent in peptide synthesis, facilitating the formation of amide bonds.
• Polymer & Material Science: Intermediate for creating fluorinated polymers, liquid crystals, and specialty materials with unique thermal and chemical resistance properties.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures.
• Derivatization Reagent: Employed in analytical chemistry for derivatizing compounds to improve detection in chromatographic methods like GC or HPLC.

Basic Information

Product Name	Sodium Pentafluorophenoxide
CAS No.	2263-53-8
Molecular Formula	C6F5NaO
Molecular Weight	214.04 g/mol
Synonyms	Pentafluorophenol Sodium Salt; Sodium Pentafluorophenolate; 2,3,4,5,6-Pentafluorophenol Sodium Salt; PFP-ONa; C6F5ONa; Sodium 2,3,4,5,6-Pentafluorophenoxide; Pentafluorosodium Phenoxide
EINECS	218-867-5

Quality Control

Our Sodium Pentafluorophenoxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.