Description

L-Canavanine Sulfate is a high-purity, non-proteinogenic amino acid derivative known for its potent biological activity. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a natural arginine antagonist. It serves as a critical tool for researchers and manufacturers in the life sciences sector, particularly for studying metabolic pathways and enzyme inhibition. The product is supplied as a sulfate salt to enhance its stability and handling properties.

Application

• Biochemical Research: Used as a specific inhibitor of nitric oxide synthase (NOS) and other arginine-utilizing enzymes to study cellular signaling and metabolic processes.
• Pharmaceutical Intermediates: Serves as a key building block or reference standard in the development of novel therapeutic agents targeting specific amino acid pathways.
• Plant Biology Studies: Employed in research to investigate plant defense mechanisms and natural product biosynthesis, given its natural occurrence in certain legume seeds.
• Microbiology & Antibiotic Research: Utilized in studies exploring antimicrobial agents and the metabolic vulnerabilities of microorganisms.
• Cell Culture & In Vitro Assays: Acts as a selective agent in cell culture media to study amino acid transport and auxotrophic cell lines.
• Diagnostic Reagent Development: Potential use in formulating specialized reagents for clinical diagnostics and enzymatic test kits.

Basic Information

Product Name	L-Canavanine Sulfate
CAS No.	2219-31-0
Molecular Formula	C5H12N4O3 • H2SO4
Molecular Weight	274.25 g/mol
Synonyms	L-(+)-Canavanine Sulfate; Canavanine Sulfate; O-[(Aminoiminomethyl)amino]-L-homoserine Sulfate; (S)-2-Amino-4-(guanidinooxy)butyric acid sulfate; Canavanine Acid Sulfate; L-α-Amino-γ-guanidinooxybutyric acid sulfate; NSC 17767; L-Canavanine, sulfate salt
EINECS	218-734-3

Quality Control

Our L-Canavanine Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and verification of sulfate content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: +16.5° to +18.5° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.