Description

L-Homoserine Lactone Hydrochloride is a high-purity chiral building block and biochemical intermediate essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical precursor for the synthesis of various natural products, amino acid derivatives, and complex heterocycles. It is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality raw materials for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of antibiotics, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in the study of quorum sensing molecules (acyl-homoserine lactones) and bacterial communication pathways.
• Peptide Synthesis: Serves as a protected form of homoserine for the solid-phase and solution-phase synthesis of modified peptides and peptidomimetics.
• Agrochemical Development: Intermediate in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Building block for creating specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Academic & Industrial R&D: Essential reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	L-Homoserine Lactone Hydrochloride
CAS No.	2185-03-7
Molecular Formula	C4H8ClNO2
Molecular Weight	137.56 g/mol
Synonyms	(S)-(-)-2-Amino-4-butyrolactone hydrochloride; L-2-Amino-4-butyrolactone hydrochloride; (S)-3-Aminodihydro-2(3H)-furanone hydrochloride; L-α-Amino-γ-butyrolactone hydrochloride; Homoserine lactone HCl; L-HSL HCl; L-HomoSer Lactone HCl; (S)-Amino-γ-butyrolactone hydrochloride
EINECS	218-562-7

Quality Control

Our L-Homoserine Lactone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided for every shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.