Description

5-Fluoro-6-Methylpyrimidin-4-Ol Hydrochloride is a high-purity pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the introduction of specific fluorine and methyl substitutions. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrimidine core for bioactivity.
• Fine Chemical Production: Serves as a versatile precursor for creating complex, fluorinated organic molecules used in material science and specialty chemistry.
• Research & Development: An important reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in medicinal chemistry.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scalable synthesis of APIs where the 5-fluoro-6-methylpyrimidin-4-ol moiety is a core structural component.

Basic Information

Product Name	5-Fluoro-6-Methylpyrimidin-4-Ol Hydrochloride
CAS No.	2145-55-3
Molecular Formula	C5H6FN3O·HCl
Molecular Weight	191.58 g/mol (Free base: 155.12 g/mol)
Synonyms	4-Hydroxy-5-fluoro-6-methylpyrimidine hydrochloride; 5-Fluoro-6-methyl-4-pyrimidinol hydrochloride; 5-Fluoro-6-methyl-4(1H)-pyrimidinone hydrochloride; 5-Fluoro-6-methylpyrimidin-4(3H)-one hydrochloride; 5-Fluoro-6-methyl-4-hydroxypyrimidine HCl; 4-Pyrimidinol, 5-fluoro-6-methyl-, hydrochloride; 2145-55-3 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methylpyrimidin-4-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.