Description

5-Chloro-2-Fluoroaniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive aromatic amine core with strategically placed halogen substituents, enabling precise molecular construction. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and stability.
• Dyestuff and Pigment Production: Serves as a starting material for synthesizing complex azo dyes and high-performance pigments.
• Liquid Crystal and OLED Material Research: Acts as a building block for creating novel organic electronic materials due to its aromatic amine functionality.
• Cross-Coupling Reactions: The halogen atoms make it a suitable substrate for palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings.
• Polymer Modification: Used to introduce aromatic amine groups into polymer chains to alter material properties.

Basic Information

Product Name	5-Chloro-2-Fluoroaniline
CAS No.	2106-05-0
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Fluoro-5-chloroaniline; 5-Chloro-2-fluoro-benzenamine; Benzenamine, 5-chloro-2-fluoro-; 2-Fluoro-5-chlorophenylamine; 5-Chloro-2-fluorophenylamine; 1-Amino-5-chloro-2-fluorobenzene; 2106-05-0; 5-Chloro-2-fluoroaniline
EINECS	218-277-4

Quality Control

Our 5-Chloro-2-Fluoroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality assurance protocols are designed to meet the stringent requirements of GMP and ISO standards where applicable, supporting our commitment to supply chain integrity for critical industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions. Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	32 - 36 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.