Description

3-Chloro-2-Fluoroaniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by research institutions for material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aniline core structure.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, where the chloro-fluoro substitution can enhance biological activity and stability.
• Dyestuff and Pigment Production: Acts as an intermediate for creating specialized azo dyes and high-performance pigments.
• Liquid Crystal & OLED Material Research: Serves as a building block for synthesizing novel organic electronic materials.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to introduce functionalized aniline groups into complex architectures.
• Chemical Research & Development: Employed as a standard reagent in academic and industrial R&D for exploring new synthetic pathways.

Basic Information

Product Name	3-Chloro-2-Fluoroaniline
CAS No.	2106-04-9
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Fluoro-3-chloroaniline; 3-Chloro-2-fluoro-benzenamine; Benzenamine, 3-chloro-2-fluoro-; 1-Amino-3-chloro-2-fluorobenzene; 3-Chloro-2-fluorophenylamine; 2-Fluoro-3-chlorophenylamine; 3-Chloro-2-fluoroaniline (primary name)
EINECS	218-277-4

Quality Control

Our 3-Chloro-2-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Clear, light yellow to amber liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.