Description

4-Bromo-2-Fluorophenol is a versatile halogenated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the phenol ring, makes it an essential intermediate for creating complex molecules with tailored properties. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the bromo-fluoro substitution pattern can enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce halogenated phenolic groups into polymer chains, altering thermal stability, flame retardancy, or other material properties.
• Organic Synthesis Reagent: A valuable reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions in research and development.
• Dye & Pigment Intermediate: Used in the production of specialized dyes and pigments where halogen atoms influence color fastness and spectral properties.

Basic Information

Product Name	4-Bromo-2-Fluorophenol
CAS No.	2105-94-4
Molecular Formula	C6H4BrFO
Molecular Weight	191.00 g/mol
Synonyms	2-Fluoro-4-bromophenol; 4-Bromo-2-fluorophenol; Phenol, 4-bromo-2-fluoro-; 4-Brom-2-fluor-phenol; 2-Fluoro-4-bromo-1-hydroxybenzene; 1-Hydroxy-4-bromo-2-fluorobenzene; 4-Bromo-2-fluoro-1-hydroxybenzene; 2105-94-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.