Description

Propofol is a short-acting, intravenous general anesthetic agent widely recognized for its rapid onset and smooth recovery profile. Its primary value lies in enabling precise control of sedation and anesthesia during medical procedures, making it a cornerstone of modern anesthetic practice. This high-purity pharmaceutical active ingredient is essential for manufacturers in the hospital and surgical sectors, specifically for formulating injectable anesthetic and sedative products.

Application

• General Anesthesia: Induction and maintenance of anesthesia for surgical and diagnostic procedures.
• Sedation in Intensive Care: Long-term sedation of intubated, mechanically ventilated adult patients.
• Procedural Sedation: For short-term sedation during minimally invasive procedures (e.g., endoscopy, colonoscopy).
• Pharmaceutical Formulation: As the active pharmaceutical ingredient (API) in injectable emulsion products.
• Neurological Research: Used in preclinical studies to investigate mechanisms of anesthesia and sedation.

Basic Information

Product Name	Propofol
CAS No.	2078-54-8
Molecular Formula	C12H18O
Molecular Weight	178.27 g/mol
Synonyms	2,6-Diisopropylphenol; Disoprofol; Diprivan (Trade Name); Propofolum; ICI 35,868; 2,6-Bis(1-methylethyl)phenol; Phenol, 2,6-bis(1-methylethyl)-
EINECS	218-206-6

Quality Control

Our Propofol is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA), detailing parameters such as assay, related substances, and residual solvents, is provided with each batch to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong alkalis and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to almost white crystalline powder or colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity ≤ 0.1%; Total impurities ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.