Description

2-Amino-4,6-Dimethyl-5-Iodopyrimidine is a halogenated pyrimidine derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its functionalized structure, which allows for selective cross-coupling reactions and further derivatization, making it essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its pyrimidine core.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Ligand Synthesis: Utilized in organometallic chemistry for the preparation of complex ligands used in catalysis.
• Chemical Biology Probe: Acts as a tagged molecular scaffold for studying biological interactions and enzyme mechanisms.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings.

Basic Information

Product Name	2-Amino-4,6-Dimethyl-5-Iodopyrimidine
CAS No.	2033-47-8
Molecular Formula	C6H8IN3
Molecular Weight	249.06 g/mol
Synonyms	5-Iodo-2-amino-4,6-dimethylpyrimidine; 4,6-Dimethyl-5-iodopyrimidin-2-amine; 5-Iodo-4,6-dimethyl-2-pyrimidinamine; 2-Pyrimidinamine, 4,6-dimethyl-5-iodo-; 5-Iodo-2-amino-4,6-dimethylpyrimidine; 4,6-Dimethyl-5-iodo-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 2-Amino-4,6-Dimethyl-5-Iodopyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and elemental analysis. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.