Description

Thiazolo[4,5-d]pyrimidine (8Ci,9Ci) is a high-purity, fused heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique bicyclic structure, incorporating both thiazole and pyrimidine rings, makes it a valuable scaffold for developing novel active pharmaceutical ingredients (APIs) and functional materials. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition, antiviral activity, and other therapeutic areas.
• Agrochemical Research: Used as a core structure for developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient heterocyclic system.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized heterocyclic dyes and colorants with specific light-absorption properties.

Basic Information

Product Name	Thiazolo[4,5-d]pyrimidine (8Ci,9Ci)
CAS No.	273-99-4
Molecular Formula	C5H3N3S
Molecular Weight	137.16 g/mol
Synonyms	Thiazolo[4,5-d]pyrimidine; [1,3]Thiazolo[4,5-d]pyrimidine; 273-99-4; Thiazolo(4,5-d)pyrimidine; NSC 51128; CCRIS 6055; 4H-Thiazolo[4,5-d]pyrimidine; 1,3-Thiazolo[4,5-d]pyrimidine
EINECS	205-997-7

Quality Control

Our Thiazolo[4,5-d]pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.