Description

7H-Pyrazolo[4,3-D]Pyrimidine (8Ci,9Ci) is a high-purity heterocyclic organic compound, serving as a critical advanced pharmaceutical intermediate and versatile chemical building block. Its fused pyrazolo-pyrimidine core structure is essential for synthesizing a wide range of bioactive molecules, particularly in medicinal chemistry. This compound is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting protein kinases for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: Serves as a core structure for developing selective enzyme inhibitors used in biochemical and pharmacological research.
• Agrochemical Development: Employed in the research and synthesis of novel active ingredients for crop protection products.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	7H-Pyrazolo[4,3-D]Pyrimidine (8Ci,9Ci)
CAS No.	272-53-7
Molecular Formula	C5H4N4
Molecular Weight	120.11 g/mol
Synonyms	7H-Pyrazolo[4,3-d]pyrimidine; Pyrazolo[4,3-d]pyrimidine; 1H-Pyrazolo[4,3-d]pyrimidine; 272-53-7; 7H-Pyrazolo(4,3-d)pyrimidine; NSC 51128; CCRIS 5951; Pyrazolo(4,3-d)pyrimidine
EINECS	205-981-5

Quality Control

Our 7H-Pyrazolo[4,3-D]Pyrimidine (8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.