Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Gly-D-Ser(Psi(Me,Me)-Pro)-Oh is a specialized, high-purity pseudoproline-containing dipeptide building block used in advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over peptide conformation and solubility, particularly for challenging sequences. It is primarily utilized in the development of novel therapeutic peptides, peptidomimetics, and biochemical research tools within the pharmaceutical and biotechnology sectors.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected pseudoproline dipeptide for introducing turn-inducing elements and improving the synthesis of difficult sequences.
• Therapeutic Peptide Development: For the research and production of peptide-based drug candidates targeting various diseases.
• Peptidomimetic Design: Serving as a crucial scaffold in creating stable, bioactive mimics of natural peptides with enhanced pharmacological properties.
• Biochemical Research: Used as a standard or reagent in studies of protein folding, structure-activity relationships (SAR), and molecular recognition.
• Pharmaceutical Intermediates: Acts as a high-value intermediate in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Gly-D-Ser(Psi(Me,Me)-Pro)-Oh
CAS No.	1998701-38-4
Molecular Formula	C26H29N3O7
Molecular Weight	495.53 g/mol
Synonyms	Fmoc-Gly-D-Ser(ψMe,Mepro)-OH; Fmoc-Gly-D-Ser(ψ(Me,Mepro))-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycyl-N-[(2S)-2-hydroxy-1-(2,2-dimethyl-1-pyrrolidinyl)propylidene]-D-serinamide; Glycyl-N-[(2S)-2-hydroxy-1-(2,2-dimethyl-1-pyrrolidinyl)propylidene]-D-serinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-Gly-D-Ser(ψMe,Mepro)-OH; Pseudoproline Dipeptide Fmoc-Gly-D-Ser(ψMe,Mepro)-OH; Fmoc-Gly-D-Ser[ψ(Me,Mepro)]-OH
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of (9H-Fluoren-9-Yl)Methoxy]Carbonyl Gly-D-Ser(Psi(Me,Me)-Pro)-Oh is characterized and controlled using advanced analytical techniques, including HPLC, NMR, and MS, to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, supporting cGMP-compliant applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere (e.g., argon or nitrogen) when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.