Description

1,4-Benzodioxin-6-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-2,3-Dihydro-, (αs)- is a sophisticated, optically active Fmoc-protected amino acid derivative designed for advanced synthetic chemistry. This compound is a critical high-purity building block for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers developing novel therapeutic agents and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of complex peptide sequences.
• Peptidomimetic Drug Discovery: Serving as a crucial intermediate in the design and synthesis of non-peptide molecules that mimic bioactive peptides.
• Pharmaceutical Intermediate: For the production of active pharmaceutical ingredients (APIs) targeting neurological and metabolic disorders.
• Bioconjugation & Probe Development: Used in the creation of labeled peptides for diagnostic assays and biochemical research.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in medicinal chemistry and chemical biology.

Basic Information

Product Name	1,4-Benzodioxin-6-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-2,3-Dihydro-, (αs)-
CAS No.	1998647-06-5
Molecular Formula	C26H23NO6
Molecular Weight	445.47 g/mol
Synonyms	(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-1,4-benzodioxin-6-propanoic Acid; Fmoc-(S)-1,4-Benzodioxane-6-Alanine; Fmoc-1,4-Benzodioxin-6-Ala-OH; Fmoc-Bdo(6)-Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,4-benzodioxane-6-alanine; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our production adheres to strict quality management systems. Every batch is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry to ensure high chemical and chiral purity suitable for sensitive pharmaceutical applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.