Description

6-Quinolinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- is a sophisticated Fmoc-protected amino acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling the precise construction of complex peptide and peptidomimetic structures, particularly those incorporating quinoline-based pharmacophores. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, agrochemical discovery, and advanced materials science who require reliable, high-quality chiral synthons for their most demanding projects.

Application

• Pharmaceutical Intermediate: A key chiral building block for the solid-phase and solution-phase synthesis of novel therapeutic peptides and peptidomimetics targeting various disease pathways.
• Drug Discovery Research: Used in medicinal chemistry programs to incorporate the quinoline moiety into candidate molecules, exploring its potential for antimicrobial, anticancer, or anti-inflammatory activity.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and specialty agrochemicals requiring specific chiral centers.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged peptide probes for studying protein-protein interactions and enzyme mechanisms.
• Material Science: Potential monomer or precursor for creating functionalized polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	6-Quinolinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)-
CAS No.	1998643-85-8
Molecular Formula	C₂₇H₂₄N₂O₄
Molecular Weight	440.49 g/mol
Synonyms	Fmoc-3-(6-Quinolyl)-L-alanine; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(quinolin-6-yl)propanoic acid; N-α-Fmoc-3-(6-quinolyl)-L-alanine; Fmoc-L-3-(6-Quinolyl)alanine; N-Fmoc-β-(6-quinolyl)-L-alanine; 6-Quinolinepropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αS)-; Fmoc-3-(6-Quinolyl)Ala-OH; Fmoc-6-Quinolyl-L-alanine
EINECS	Contact for details

Quality Control

Our production of 6-Quinolinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and cGMP applications. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.