Description

4-Quinolinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- is a specialized, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic syntheses. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel active pharmaceutical ingredients (APIs) and sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase peptide synthesis (SPPS) as a protected amino acid derivative, facilitated by the Fmoc (9-fluorenylmethoxycarbonyl) protecting group.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the discovery of new therapeutic agents.
• Bioconjugation: Employed in the chemical modification of biomolecules for drug delivery systems and diagnostic probes.
• Fine Chemical Production: Acts as a precursor in the manufacture of high-value, specialized chemicals for research and industrial applications.
• Academic & Industrial R&D: Essential for synthetic organic chemistry projects in university laboratories and corporate R&D centers exploring new molecular entities.

Basic Information

Product Name	4-Quinolinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)-
CAS No.	1998513-62-4
Molecular Formula	C27H24N2O4
Molecular Weight	440.49 g/mol
Synonyms	Fmoc-Asn(4-Quinolyl)-OH; (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(quinolin-4-yl)propanoic acid; N-α-Fmoc-N-δ-(4-quinolyl)-L-asparagine; Fmoc-L-Asn(4-Quin)-OH; Fmoc-Asn(Quin-4)-OH; N-α-(9-Fluorenylmethoxycarbonyl)-N-δ-(4-quinolyl)-L-asparagine; L-Asn(4-Quinolyl)-OH, N-α-Fmoc-; 4-Quinolinyl-L-asparagine N-α-Fmoc derivative
EINECS	Contact for details

Quality Control

Our production of 4-Quinolinepropanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.