Description

Methyl 2,6-Difluoro-5-Formylbenzoate is a high-value fluorinated aromatic building block, essential for the synthesis of complex molecules in advanced research and development. Its unique structure, featuring both a formyl and an ester group on a difluorinated benzene ring, makes it a versatile intermediate for constructing pharmacologically active scaffolds. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, where its fluorine atoms and reactive handles are critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the difluoro motif enhances stability and bioavailability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or optical properties.
• Chemical Biology & Proteomics: Utilized as a derivatization agent or a scaffold for designing molecular probes and enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise fluorination patterns.

Basic Information

Product Name	Methyl 2,6-Difluoro-5-Formylbenzoate
CAS No.	1993479-30-3
Molecular Formula	C9H6F2O3
Molecular Weight	200.14 g/mol
Synonyms	5-Formyl-2,6-difluorobenzoic Acid Methyl Ester; Methyl 5-Formyl-2,6-difluorobenzoate; 2,6-Difluoro-5-formylbenzoic Acid Methyl Ester; Benzoic acid, 2,6-difluoro-5-formyl-, methyl ester; Methyl 2,6-difluoro-5-formylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,6-Difluoro-5-Formylbenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.