Description

(2S)-3-Cycloheptyl-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid is a specialized, high-purity amino acid derivative featuring a cycloheptyl side chain and an Fmoc-protected amine group. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, enabling the introduction of unique structural motifs. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in drug discovery and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid for the automated or manual assembly of custom peptide sequences.
• Peptidomimetic Drug Discovery: Incorporation into non-natural peptide backbones to enhance metabolic stability, bioavailability, and target binding affinity.
• Chemical Biology Research: Used as a probe or tool compound to study protein-protein interactions and enzyme mechanisms.
• API Intermediate Manufacturing: Serves as a key chiral intermediate in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
• Libraries for High-Throughput Screening (HTS): A valuable component for generating diverse compound libraries to identify new lead molecules.

Basic Information

Product Name	(2S)-3-Cycloheptyl-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid
CAS No.	1993342-75-8
Molecular Formula	C25H29NO4
Molecular Weight	407.50 g/mol
Synonyms	Fmoc-Cycloheptylalanine-OH; Fmoc-Cha-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-cycloheptyl-L-alanine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-cycloheptylpropanoic acid; Fmoc-L-3-cycloheptylalanine; Nα-Fmoc-cycloheptyl-L-alanine; Fmoc-Cha; Fmoc-C7Ala-OH
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and purified to meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity confirmation, and impurity profiles to ensure batch-to-batch consistency and reliability for your critical syntheses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.