Description

Fmoc-(S)-3-Amino-4-(3-Bromo-Phenyl)-Butyric Acid is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for the research and development of novel peptide-based pharmaceuticals and biochemical tools. It is primarily utilized by medicinal chemists and researchers in the pharmaceutical, biotechnology, and life sciences industries for constructing complex peptide sequences with specific structural and functional properties.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy, enabling the controlled assembly of custom peptides.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the development of peptide drug candidates, including enzyme inhibitors and receptor modulators.
• Peptidomimetic Research: Used to incorporate a bromo-phenyl side chain into peptide backbones, exploring structure-activity relationships (SAR) and enhancing metabolic stability.
• Chemical Biology Probes: Facilitates the synthesis of labeled or modified peptides for studying protein-protein interactions and cellular pathways.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse peptide libraries in high-throughput screening for drug discovery.
• API Development: Employed in the research-scale synthesis of Active Pharmaceutical Ingredients (APIs) with complex peptide motifs.

Basic Information

Product Name	Fmoc-(S)-3-Amino-4-(3-Bromo-Phenyl)-Butyric Acid
CAS No.	1956435-50-9
Molecular Formula	C25H22BrNO4
Molecular Weight	480.35 g/mol
Synonyms	Fmoc-3-Amino-4-(3-bromophenyl)butanoic acid; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(3-bromophenyl)butanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-4-(3-bromophenyl)butyric acid; Fmoc-3-Abz(3-Br)-OH; Fmoc-(S)-Amino(3-bromobenzyl)acetic acid; N-α-Fmoc-3-amino-4-(3-bromophenyl)butyric acid
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-3-Amino-4-(3-Bromo-Phenyl)-Butyric Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, chiral integrity, and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.