Description

8-(Bicyclo[3.1.0]Hexan-2-Yl)-2-Chloro-5-Methylpyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a structurally complex scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Used in the research and production of potential kinase inhibitors due to the pyridopyrimidinone core structure.
• Oncology Drug Candidates: Employed in the development of preclinical and clinical-stage compounds for cancer therapeutics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and novel heterocyclic chemistry exploration.

Basic Information

Product Name	8-(Bicyclo[3.1.0]Hexan-2-Yl)-2-Chloro-5-Methylpyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	1956382-99-2
Molecular Formula	C17H16ClN3O
Molecular Weight	313.78 g/mol
Synonyms	2-Chloro-5-methyl-8-(bicyclo[3.1.0]hexan-2-yl)pyrido[2,3-d]pyrimidin-7(8H)-one; 8-(Bicyclo[3.1.0]hexan-2-yl)-2-chloro-5-methyl-7,8-dihydropyrido[2,3-d]pyrimidin-7-one; 1956382-99-2; Bicyclo[3.1.0]hexane-pyridopyrimidinone derivative; 2-Chloro-5-methyl-8-(norbornan-2-yl)pyrido[2,3-d]pyrimidin-7-one (related); SCHEMBL23583019; AKOS040750623; A-1598
EINECS	Contact for details

Quality Control

Our 8-(Bicyclo[3.1.0]Hexan-2-Yl)-2-Chloro-5-Methylpyrido[2,3-D]Pyrimidin-7(8H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent specifications for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure maximum stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.