Description

8-Bromo-2,4,6-Trichloroquinazoline is a high-value halogenated quinazoline derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with precise functionalization. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly in medicinal chemistry for kinase inhibitor research and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase-targeted therapies and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and heterocyclic compound synthesis.
• Custom Synthesis: Acts as a starting material for contract research organizations (CROs) and CDMOs to produce bespoke compounds for client projects.

Basic Information

Product Name	8-Bromo-2,4,6-Trichloroquinazoline
CAS No.	1956375-12-4
Molecular Formula	C8H2BrCl3N2
Molecular Weight	326.37 g/mol
Synonyms	2,4,6-Trichloro-8-bromoquinazoline; 8-Bromo-2,4,6-trichloro-quinazoline; Quinazoline, 8-bromo-2,4,6-trichloro-; BTQ; 8-Br-2,4,6-Cl3-Quinazoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,4,6-Trichloroquinazoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.