Description

3-(Trifluoromethyl)Quinoline-7-Sulfonyl Chloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in the reactive sulfonyl chloride group, which enables efficient coupling reactions to create complex sulfonamide and sulfonate derivatives. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Building block for creating functional polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) and affinity labels for target protein identification.
• Custom Synthesis & Contract Manufacturing: Serves as a critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-(Trifluoromethyl)Quinoline-7-Sulfonyl Chloride
CAS No.	1956332-63-0
Molecular Formula	C₁₀H₅ClF₃NO₂S
Molecular Weight	295.66 g/mol
Synonyms	7-Sulfonylchloride-3-(trifluoromethyl)quinoline; 3-Trifluoromethylquinoline-7-sulfonyl chloride; Quinoline-7-sulfonyl chloride, 3-(trifluoromethyl)-; 7-Chlorosulfonyl-3-(trifluoromethyl)quinoline; 3-(Trifluoromethyl)-7-quinolinesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Quinoline-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports our clients' needs for regulatory compliance in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.