Description

N2-(4-Bromobenzyl)-5-Fluoro-N4-Phenylpyrimidine-2,4-Diamine (Wxc02286) is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1956306-82-3. This compound is a critical building block in modern medicinal chemistry, valued for its role in the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in biochemical assays to study enzyme inhibition mechanisms and cellular signaling pathways.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Employed in university laboratories for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	N2-(4-Bromobenzyl)-5-Fluoro-N4-Phenylpyrimidine-2,4-Diamine (Wxc02286)
CAS No.	1956306-82-3
Molecular Formula	C17H14BrFN4
Molecular Weight	373.23 g/mol
Synonyms	WXC-02286; Wxc02286; 5-Fluoro-N2-[(4-bromophenyl)methyl]-N4-phenyl-2,4-pyrimidinediamine; N-(4-Bromobenzyl)-5-fluoro-N'-phenylpyrimidine-2,4-diamine; 2,4-Pyrimidinediamine, 5-fluoro-N2-[(4-bromophenyl)methyl]-N4-phenyl-; 1956306-82-3
EINECS	Contact for details

Quality Control

Our N2-(4-Bromobenzyl)-5-Fluoro-N4-Phenylpyrimidine-2,4-Diamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and LC-MS. We are committed to meeting the stringent requirements of GMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.