Description

3-Fluoro-6-Iodo-2-Nitroaniline is a halogenated nitroaniline derivative, a key fluorinated and iodinated aromatic amine building block. This compound matters for its unique molecular architecture, offering multiple reactive sites for selective functionalization in complex organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A versatile synthon for the development of fluorinated and iodinated drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the fluorine and iodine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functional dyes, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and halogen groups.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to build complex biaryl structures.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry for generating diverse compound libraries for biological screening.
• Fluorine Chemistry Studies: Acts as a model compound in studying the electronic effects of *ortho*-substituted fluorine atoms in aromatic systems.

Basic Information

Product Name	3-Fluoro-6-Iodo-2-Nitroaniline
CAS No.	1955534-80-1
Molecular Formula	C6H4F I N2O2
Molecular Weight	282.01 g/mol
Synonyms	2-Nitro-3-fluoro-6-iodoaniline; 3-Fluoro-2-nitro-6-iodoaniline; 6-Iodo-3-fluoro-2-nitroaniline; 1-Amino-3-fluoro-6-iodo-2-nitrobenzene; 2-Amino-4-fluoro-3-iodonitrobenzene; Benzenamine, 3-fluoro-6-iodo-2-nitro-; (3-Fluoro-6-iodo-2-nitrophenyl)amine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-6-Iodo-2-Nitroaniline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, and residual solvents is provided and available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.