Description

n-(2-Amino-3-Fluorophenyl)Methanesulfonamide is a specialized aromatic sulfonamide derivative featuring both amino and fluoro substituents, making it a valuable synthetic intermediate. This compound is engineered to serve as a key building block in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of targeted small-molecule drugs, particularly those acting on central nervous system (CNS) targets or as kinase inhibitors.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the sulfonamide and fluorophenyl motifs.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biochemical research.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	n-(2-Amino-3-Fluorophenyl)Methanesulfonamide
CAS No.	1951441-66-9
Molecular Formula	C7H9FN2O2S
Molecular Weight	204.22 g/mol
Synonyms	2-Amino-3-fluorobenzenesulfonamide; 3-Fluoro-2-aminobenzenesulfonamide; Methanesulfonamide, N-(2-amino-3-fluorophenyl)-; 1-Amino-2-fluoro-6-(methylsulfonyl)benzene; N1-(2-Amino-3-fluorophenyl)methanesulfonamide; 2-Fluoro-6-(methylsulfonyl)aniline
EINECS	Contact for details

Quality Control

Our n-(2-Amino-3-Fluorophenyl)Methanesulfonamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.