Description

Fmoc-Thr(Allyl)-Oh is a protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound provides a crucial building block for the controlled assembly of complex peptides and proteins, enabling precise chemical manipulation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, peptide therapeutics, and biochemical research.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential addition of amino acids using Fmoc-chemistry protocols.
• Peptide Drug Discovery: Used in the research and development of novel therapeutic peptides targeting various diseases.
• Bioconjugation: The allyl-protected side chain allows for selective deprotection and subsequent modification or labeling of peptides.
• Combinatorial Chemistry: Serves as a building block in libraries for high-throughput screening of bioactive compounds.
• Academic & Industrial Research: Fundamental reagent for studying protein structure-function relationships and enzyme mechanisms.
• Custom Peptide Service Providers: A critical raw material for companies offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-Thr(Allyl)-Oh
CAS No.	1945973-89-6
Molecular Formula	C₂₂H₂₃NO₅
Molecular Weight	381.42 g/mol
Synonyms	Fmoc-O-tert-butyl-L-threonine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-propen-1-yl)-L-threonine; Fmoc-L-threonine(allyl)-OH; Fmoc-Thr(All)-OH; (2S,3R)-3-(Allyloxy)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid; N-Fmoc-O-allyl-L-threonine; Fmoc-Thr(Allyl)-OH; Allyl O-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonyl] ether
EINECS	Contact for details

Quality Control

Our Fmoc-Thr(Allyl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for sensitive peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.