Description

1,3-Benzenediamine, 4,6-Dimethoxy-N1-[4-(1-Methyl-1H-Indol-3-Yl)-2-Pyrimidinyl]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key structural motif for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on oncology, antiviral, and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	1,3-Benzenediamine, 4,6-Dimethoxy-N1-[4-(1-Methyl-1H-Indol-3-Yl)-2-Pyrimidinyl]-
CAS No.	1942853-79-3
Molecular Formula	C21H21N5O2
Molecular Weight	375.43 g/mol
Synonyms	4,6-Dimethoxy-N1-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,3-benzenediamine; 4,6-Dimethoxy-N1-[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]benzene-1,3-diamine; 2-(2,4-Diamino-3,5-dimethoxyphenyl)-N-(1-methyl-1H-indol-3-yl)pyrimidin-4-amine; 4-(1-Methyl-1H-indol-3-yl)-2-(3,5-dimethoxy-1,4-phenylenediamino)pyrimidine; 1,3-Benzenediamine, 4,6-dimethoxy-N-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-; 1942853-79-3; 4,6-Dimethoxy-m-phenylenediamine derivative
EINECS	Contact for details

Quality Control

Our 1,3-Benzenediamine, 4,6-Dimethoxy-N1-[4-(1-Methyl-1H-Indol-3-Yl)-2-Pyrimidinyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.