Description

2-Bromo-3-Fluoro-4-Iodoaniline is a high-purity, multi-halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to develop new herbicides, fungicides, and pesticides by introducing halogenated aniline motifs into lead structures.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, enabling complex molecular architecture.
• Dye & Pigment Industry: Intermediate for synthesizing specialized halogenated azo dyes and pigments with enhanced lightfastness and color properties.
• Academic & R&D: Essential tool in university and corporate research laboratories for exploring new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	2-Bromo-3-Fluoro-4-Iodoaniline
CAS No.	1936364-85-0
Molecular Formula	C6H4BrFIN
Molecular Weight	315.91 g/mol
Synonyms	4-Amino-2-bromo-3-fluoro-1-iodobenzene; 1-Amino-2-bromo-3-fluoro-4-iodobenzene; 2-Bromo-3-fluoro-4-iodobenzenamine; Benzenamine, 2-bromo-3-fluoro-4-iodo-; Aniline, 2-bromo-3-fluoro-4-iodo-; 4-Iodo-2-bromo-3-fluoroaniline
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Fluoro-4-Iodoaniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.