Description

4-{[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}-1,4-Oxazepane-6-Carboxylic Acid is a specialized heterocyclic building block designed for advanced organic synthesis. This compound is of significant value in pharmaceutical research and development, particularly in the synthesis of complex molecules and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in peptide mimetics, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry & Mimetics: Used in the construction of peptide-like structures and peptidomimetics due to its oxazepane carboxylic acid scaffold.
• Solid-Phase Peptide Synthesis (SPPS): The Fmoc-protected amine group makes it suitable for use in Fmoc-based SPPS protocols.
• Medicinal Chemistry Research: Serves as a versatile intermediate for creating focused libraries of compounds for biological screening.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.

Basic Information

Product Name	4-{[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}-1,4-Oxazepane-6-Carboxylic Acid
CAS No.	1936071-00-9
Molecular Formula	C21H21NO5
Molecular Weight	367.40 g/mol
Synonyms	Fmoc-1,4-oxazepane-6-carboxylic acid; 4-[(9-Fluorenylmethoxycarbonyl)]-1,4-oxazepane-6-carboxylic acid; 6-Carboxy-1,4-oxazepane-4-carboxylic acid 9H-fluoren-9-ylmethyl ester; 1,4-Oxazepane-6-carboxylic acid, 4-[[(9H-fluoren-9-yl)methoxy]carbonyl]-; Fmoc-Aze(6)-OH (related to azepane derivatives); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-{[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}-1,4-Oxazepane-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.