Description

2-Cyclopropyl-4-(Trifluoromethyl)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl-substituted aniline core. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic electronic materials due to its unique electronic properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	2-Cyclopropyl-4-(Trifluoromethyl)Aniline
CAS No.	1936063-39-6
Molecular Formula	C10H10F3N
Molecular Weight	201.19 g/mol
Synonyms	2-Cyclopropyl-4-(trifluoromethyl)benzenamine; 4-(Trifluoromethyl)-2-cyclopropylaniline; 2-Cyclopropyl-4-trifluoromethylaniline; Benzenamine, 2-cyclopropyl-4-(trifluoromethyl)-; 2-CPA-TFMA; 2-Cyclopropyl-α,α,α-trifluoro-p-toluidine
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-4-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and internal quality standards. Custom purity grades, including research and GMP grades, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere such as nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.