Description

3-Bromo-5,7-Dichloro-1H-Pyrazolo[4,3-D]Pyrimidine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a critical intermediate for the development of novel pharmaceutical compounds, particularly kinase inhibitors and other targeted therapeutics. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex halogenated motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, especially in oncology and antiviral research.
• Kinase Inhibitor Scaffold: Used to construct core structures for novel protein kinase inhibitors due to the pyrazolopyrimidine pharmacophore.
• Agrochemical Research: Serves as a building block for developing new active ingredients with herbicidal or pesticidal properties.
• Chemical Biology Probes: Utilized in creating tool compounds for studying enzyme function and cellular signaling pathways.
• Material Science: Potential precursor for specialty chemicals and functional materials requiring specific halogenated heterocycles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development.

Basic Information

Product Name	3-Bromo-5,7-Dichloro-1H-Pyrazolo[4,3-D]Pyrimidine
CAS No.	1934543-12-0
Molecular Formula	C5HBrCl2N4
Molecular Weight	267.90 g/mol
Synonyms	3-Bromo-5,7-dichloro-1H-pyrazolo[4,3-d]pyrimidine; 1H-Pyrazolo[4,3-d]pyrimidine, 3-bromo-5,7-dichloro-; 5,7-Dichloro-3-bromo-1H-pyrazolo[4,3-d]pyrimidine; 3-Bromo-5,7-dichloro-1H-pyrazolo[4,3-d]pyrimidine; Bromodichloropyrazolopyrimidine; Pyrazolo[4,3-d]pyrimidine, 3-bromo-5,7-dichloro-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5,7-Dichloro-1H-Pyrazolo[4,3-D]Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry characterization. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.