Description

(tert-Butoxy)Carbonyl L-Dbu(Fmoc)-Oh is a high-purity, protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise, high-yield coupling in the construction of complex peptide chains. It is an essential building block for the pharmaceutical, biotechnology, and life science research industries, enabling the development of novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy, facilitating the sequential assembly of peptides on resin.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Used in the site-specific modification of proteins and other biomolecules for drug delivery and diagnostic applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Peptidomimetic Research: Integral for creating modified peptide structures with enhanced stability, bioavailability, or receptor affinity.
• Academic & Industrial R&D: A fundamental reagent for synthetic chemistry and biochemistry laboratories exploring peptide structure and function.

Basic Information

Product Name	(tert-Butoxy)Carbonyl L-Dbu(Fmoc)-Oh
CAS No.	1931961-73-7
Molecular Formula	C25H30N2O6
Molecular Weight	454.52 g/mol
Synonyms	Fmoc-L-Dbu(Boc)-OH; Nα-Fmoc-Nδ-Boc-L-2,4-diaminobutanoic acid; Nα-(9-Fluorenylmethoxycarbonyl)-Nδ-(tert-butoxycarbonyl)-L-2,4-diaminobutyric acid; Boc-Dbu(Fmoc)-OH; Fmoc-Dab(Boc)-OH; L-Dbu(Fmoc,Boc)-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl L-Dbu(Fmoc)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and cGMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards to guarantee the material's integrity for sensitive peptide synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.