Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Thr-Oh is a specialized, high-purity amino acid derivative designed for advanced synthetic chemistry. This compound matters as a critical building block for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in the fields of oncology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of N-methylated D-threonine residues.
• Protease Inhibitor Development: Serves as a core component in creating potent and selective inhibitors for various proteolytic enzymes.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the design of bioactive molecular probes.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory medicinal chemistry projects.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Thr-Oh
CAS No.	1931907-74-2
Molecular Formula	C20H21NO5
Molecular Weight	355.39 g/mol
Synonyms	Fmoc-N-Me-D-Thr-OH; Fmoc-N-methyl-D-threonine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-threonine; (2R,3S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl](methyl)amino]-3-hydroxybutanoic acid; Nα-Fmoc-N-methyl-D-threonine; N-Fmoc-N-Me-D-Thr-OH; Fmoc-D-N-methylthreonine; Fmoc-N-Me-Thr(D)-OH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl n-Me-D-Thr-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical and chiral purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.