Description

(Des-Gly10,D-Ser4,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh is a synthetic peptide analog of Gonadotropin-Releasing Hormone (GnRH), designed for enhanced stability and targeted biological activity. This compound is critical for advanced research and development in endocrinology and reproductive medicine, offering a valuable tool for studying hormone-receptor interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel GnRH-based therapeutics.
• Endocrinology Studies: Used in vitro and in vivo to investigate the mechanisms of gonadotropin release and the hypothalamic-pituitary-gonadal axis.
• Biochemical Assay Development: Employed as a critical component in the validation and calibration of diagnostic assays and receptor binding studies.
• Preclinical Studies: Utilized in animal models to evaluate the efficacy and pharmacokinetics of potential treatments for hormone-dependent conditions.
• Peptide Chemistry & Manufacturing: Acts as an intermediate or finished product for companies specializing in custom peptide synthesis for research and clinical trials.

Basic Information

Item	Detail
Product Name	(Des-Gly10,D-Ser4,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh
CAS No.	1926163-21-4
Molecular Formula	C58H82N16O13
Molecular Weight	~1211.4 g/mol
Synonyms	GnRH Analog; LHRH Analog; (Des-Gly10,D-Ser(tBu)6,Pro-NHEt9)-LHRH; Gonadorelin Analog; Luteinizing Hormone-Releasing Hormone Analog; pGlu-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt; Custom Peptide 1926163-21-4
EINECS	Contact for details

Quality Control

Our (Des-Gly10,D-Ser4,D-Ser(Tbu)6,Pro-Nhet9)-Lhrh is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.