Description

Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Nh2 is a synthetic, fluorescently-labeled peptide sequence designed for advanced biochemical research and development. This compound matters for its utility as a highly specific substrate or probe in enzymatic assays, particularly for studying protease activity and protein-protein interactions. It is primarily needed by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on enzymology, biomarker discovery, and high-throughput screening.

Application

• Protease/Enzyme Substrate: Used as a specific, fluorogenic substrate for the study of protease kinetics, inhibition, and characterization.
• Biochemical Assay Development: Serves as a critical component in the development of sensitive fluorescence-based assays for drug discovery platforms.
• Cell Biology Research: Employed as a molecular probe to visualize and track specific enzymatic activity within cellular systems.
• Diagnostic Reagent Intermediate: Acts as a key raw material in the synthesis of reagents for clinical diagnostic tests targeting specific proteolytic enzymes.
• Peptide Library Screening: Used in peptide library arrays to identify sequences with optimal binding or cleavage properties for target enzymes.
• Quality Control Standard: Functions as a reference standard in the quality control of enzyme preparations and related biopharmaceuticals.

Basic Information

Product Name	Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Nh2
CAS No.	1926163-18-9
Molecular Formula	C58H95N23O14
Molecular Weight	1290.5 g/mol
Synonyms	7-Methoxycoumarin-4-acetyl-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-amide; Mca-GAK(Ac)RHRKV-NH2; Fluorogenic Peptide Substrate Mca-GAK(Ac)RHRKV-NH2; (7-Methoxycoumarin-4-yl)acetyl-Gly-Ala-Nε-acetyl-Lys-Arg-His-Arg-Lys-Val-amide; AMC-based Peptide Substrate; Protease Substrate 1926163-18-9; Fluorescent Peptide Probe
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Mca-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Nh2 is characterized by HPLC, MS, and NMR to confirm identity and purity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We adhere to cGMP guidelines for the production of research-grade biochemicals to ensure batch-to-batch consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be kept under desiccant. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.