Description

Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-Nh2 (Disulfide Bond) is a synthetic peptide featuring a critical intramolecular disulfide bridge that stabilizes its bioactive conformation. This compound is of significant interest for advanced research in biochemistry and pharmacology, particularly in the study of protein-protein interactions and receptor binding motifs. It is primarily utilized by biotechnology and pharmaceutical R&D teams for applications in drug discovery, structural biology, and as a reference standard.

Application

• Biochemical Research: Used as a model peptide to study the structure-function relationship of disulfide-bonded domains in proteins.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery and optimization of peptide-based therapeutics.
• Proteomics & Diagnostics: Employed in assay development, antibody production, and as a calibrant in mass spectrometry-based analyses.
• Cell Signaling Studies: Investigated for its potential role in modulating specific biological pathways and cellular processes.
• Academic Research: A valuable tool for universities and research institutes conducting fundamental studies in peptide chemistry and molecular biology.

Basic Information

Product Name	Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-Nh2 (Disulfide Bond)
CAS No.	1926163-13-4
Molecular Formula	C99H145N29O31S2
Molecular Weight	2261.55 g/mol
Synonyms	Ac-ALDCDDPRVD-RWYCQFVEG-NH2 (Disulfide bond: Cys3-Cys14); Acetyl-ALA-LEU-CYS-ASP-ASP-PRO-ARG-VAL-ASP-ARG-TRP-TYR-CYS-GLN-PHE-VAL-GLU-GLY-amide (cyclic 3-14); Cyclic Ac-ALDCDDPRVD-RWYCQFVEG-NH2; Synthetic Peptide 1926163-13-4; Ac-ALCDDPRVD-RWYCQFVEG-NH2 (S-S bridge); Acetylated Peptide with Intramolecular Disulfide Bond; Research Peptide CAS 1926163-13-4
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-Nh2 (Disulfide Bond) undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the material under an inert atmosphere or in a desiccated freezer.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.