Description

Glycine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-α-Aspartyl-n-[(2-Hydroxy-4-Methoxyphenyl)Methyl]-, 1-(1,1-Dimethylethyl) Ester is a sophisticated, high-purity protected amino acid derivative designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex peptide synthesis and pharmaceutical development. It is primarily utilized in the research and production of novel therapeutic peptides, peptidomimetics, and other bioactive molecules where the protection of specific functional groups is essential.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of custom peptides, particularly those containing D-aspartic acid.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of new drug candidates, especially in oncology, neurology, and metabolic disease research.
• Peptidomimetic Design: Serves as a crucial scaffold for creating stable, bioavailable molecules that mimic natural peptides.
• Bioconjugation and Labeling: Facilitates the site-specific attachment of probes, tags, or other molecules to peptides for diagnostic or therapeutic purposes.
• Process Development & Scale-Up: Supports the transition from laboratory-scale research to commercial manufacturing of peptide-based Active Pharmaceutical Ingredients (APIs).
• Academic & Institutional Research: Enables fundamental studies in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Glycine, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-α-Aspartyl-n-[(2-Hydroxy-4-Methoxyphenyl)Methyl]-, 1-(1,1-Dimethylethyl) Ester
CAS No.	1926163-00-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-D-Asp(2-Hydroxy-4-methoxybenzyl)-OtBu; Fmoc-D-Asp(Hmb)-OtBu; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-α-aspartyl-N-[(2-hydroxy-4-methoxyphenyl)methyl]glycine 1,1-dimethylethyl ester; D-Aspartic acid, N-[N-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-α-aspartyl]-N-[(2-hydroxy-4-methoxyphenyl)methyl]glycyl]-, 1,1-dimethylethyl ester; Fmoc-D-Asp(O-2-Hydroxy-4-methoxybenzyl)-OtBu; Protected D-Aspartic Acid Derivative; Fmoc-Asp(Hmb)-OH OtBu ester (D-form)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity essential for sensitive synthetic workflows. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient humidity or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.