Description

Fmoc-D-Asp(Ompe)-Oh is a protected, non-natural amino acid derivative specifically engineered for advanced peptide synthesis. This compound is a critical building block for researchers and manufacturers developing novel peptide-based pharmaceuticals and biochemical tools. It is primarily utilized by pharmaceutical R&D teams, CROs/CDMOs, and academic institutions focused on creating complex peptide sequences with enhanced stability and bioactivity.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of modified aspartic acid residues into peptide chains using Fmoc-chemistry protocols.
• Peptidomimetic Drug Discovery: Used in the research and development of peptide-like molecules designed to mimic natural peptides for therapeutic applications, such as enzyme inhibitors or receptor agonists/antagonists.
• Bioconjugation and Linker Chemistry: Serves as a specialized component for creating peptide-drug conjugates or attaching peptides to other molecules, surfaces, or solid supports.
• Structure-Activity Relationship (SAR) Studies: Enables the systematic modification of peptide backbones to study the effect of specific structural changes on biological activity and pharmacokinetic properties.
• Production of Custom Peptides: Essential for contract manufacturing organizations (CMOs) producing bespoke peptides for research, diagnostic, or pre-clinical development purposes.

Basic Information

Product Name	Fmoc-D-Asp(Ompe)-Oh
CAS No.	1926162-97-1
Molecular Formula	C24H27NO7
Molecular Weight	441.48 g/mol
Synonyms	Fmoc-D-Aspartic acid β-(4-methoxyphenyl) ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-aspartic acid 4-methoxyphenyl ester; Fmoc-D-Asp(OMPE)-OH; Fmoc-D-Asp(OMpe)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)succinic acid 4-methoxyphenyl ester; D-Fmoc-Aspartic acid 4-methoxyphenyl ester; Fmoc-D-Asp(OCH2C6H4OCH3)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-D-Asp(Ompe)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.