Description

2,4,7-Trichloro-5H-Pyrrolo[3,2-D]Pyrimidine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core pyrrolopyrimidine scaffold, functionalized with reactive chlorine atoms, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active small molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Chemical Synthesis: The reactive chlorine sites allow for sequential functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions, enabling rapid library synthesis for drug discovery.
• Bioconjugation & Probe Development: Can be utilized to create chemical probes or linkers for bioconjugation applications in diagnostic and biochemical research.

Basic Information

Product Name	2,4,7-Trichloro-5H-Pyrrolo[3,2-D]Pyrimidine
CAS No.	1923177-10-9
Molecular Formula	C6H2Cl3N3
Molecular Weight	214.46 g/mol
Synonyms	2,4,7-Trichloro-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidine, 2,4,7-trichloro-; 2,4,7-Trichloro-7H-pyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidine, 2,4,7-trichloro-5H-; CAS 1923177-10-9
EINECS	Contact for details

Quality Control

Our 2,4,7-Trichloro-5H-Pyrrolo[3,2-D]Pyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.