Description

3-Trifluoromethyl-Benzene-1,2-Diamine Dihydrochloride is a high-purity, dihydrochloride salt derivative of a fluorinated aromatic diamine, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the trifluoromethyl group and diamine functionality, which are pivotal for modulating the physicochemical properties of target molecules. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bioactive molecules, including potential kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Functional Material Development: Building block for polymers, ligands, and metal-organic frameworks (MOFs) requiring specific fluorine-containing aromatic architectures.
• Chemical Research & Development: Essential reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized fluorinated dyes and pigments.

Basic Information

Product Name	3-Trifluoromethyl-Benzene-1,2-Diamine Dihydrochloride
CAS No.	1923042-95-8
Molecular Formula	C7H8F3N2 • 2HCl
Molecular Weight	267.07 g/mol (Free base: 176.15 g/mol)
Synonyms	3-(Trifluoromethyl)benzene-1,2-diamine dihydrochloride; 3-Trifluoromethyl-o-phenylenediamine dihydrochloride; 1,2-Diamino-3-(trifluoromethyl)benzene dihydrochloride; 3-TFM-1,2-BDA • 2HCl; 3-CF3-1,2-phenylenediamine dihydrochloride; 3-Trifluoromethyl-1,2-benzenediamine dihydrochloride; 3-Trifluoromethyl-1,2-diaminobenzene dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Trifluoromethyl-Benzene-1,2-Diamine Dihydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications, which are aligned with industry best practices for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.