Description

1H-Pyrazole-1-Propanamide, β-Cyclopentyl-4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1911644-32-0. This compound is of significant commercial interest for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for oncology and immunology targets.
• Kinase Inhibitor Development: Used extensively in medicinal chemistry research for constructing core scaffolds of potent and selective kinase inhibitors.
• Biochemical Research: Employed as a reference standard or a probe molecule in high-throughput screening and structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom compounds for client drug discovery programs.
• Process Chemistry: Utilized in route scouting and optimization for scalable GMP manufacturing of clinical trial materials.

Basic Information

Product Name	1H-Pyrazole-1-Propanamide, β-Cyclopentyl-4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-
CAS No.	1911644-32-0
Molecular Formula	C17H21N5O
Molecular Weight	311.39 g/mol
Synonyms	β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanamide; 4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-β-cyclopentyl-1H-pyrazole-1-propanamide; 1H-Pyrazole-1-propanamide, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-; UNII-8V8S8X8Q4B; 8V8S8X8Q4B; BCPPP; CAS 1911644-32-0
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-1-Propanamide, β-Cyclopentyl-4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and pre-clinical use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.