Description

Pyrido[2,3-D]Pyrimidin-7-Amine, 6-Bromo-2-Chloro-5-Methyl- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its precise molecular architecture, which serves as a critical scaffold for developing novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the development of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly for oncology and inflammatory diseases.
• Kinase Inhibitor Research: Serves as a core scaffold for designing and synthesizing potent and selective kinase inhibitors due to the pyridopyrimidine structure.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead compounds.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions in cellular assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity heterocyclic chemistry.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and new synthetic methodology development.

Basic Information

Product Name	Pyrido[2,3-D]Pyrimidin-7-Amine, 6-Bromo-2-Chloro-5-Methyl-
CAS No.	1908455-60-6
Molecular Formula	C8H6BrClN4
Molecular Weight	273.52 g/mol
Synonyms	6-Bromo-2-chloro-5-methylpyrido[2,3-d]pyrimidin-7-amine; 6-Bromo-2-chloro-5-methyl-7H-pyrido[2,3-d]pyrimidin-7-amine; 7H-Pyrido[2,3-d]pyrimidin-7-amine, 6-bromo-2-chloro-5-methyl-; 1908455-60-6; 6-Bromo-2-chloro-5-methyl-pyrido[2,3-d]pyrimidin-7-ylamine
EINECS	Contact for details

Quality Control

Our production of Pyrido[2,3-D]Pyrimidin-7-Amine, 6-Bromo-2-Chloro-5-Methyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive pharmaceutical R&D. All material is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We operate under a quality system aligned with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.