Description

Z-Arg(Boc)2-OH·Cha is a high-purity, protected arginine derivative, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for constructing complex peptide sequences where the guanidine group of arginine requires orthogonal protection to prevent side reactions. It serves as an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of arginine residues using Fmoc/t-Bu or Boc/Bzl strategies.
• Solution-Phase Peptide Synthesis: Used in the synthesis of longer or more complex peptide chains in solution, offering flexibility in coupling and deprotection steps.
• Pharmaceutical Intermediate: Serves as a critical raw material in the production of active pharmaceutical ingredients (APIs) for peptide-based drugs targeting various diseases.
• Bioconjugation and Labeling: The protected functional groups allow for selective modification, making it useful for creating labeled peptides for imaging or diagnostic purposes.
• Research & Development: Employed in academic and industrial R&D for exploring new peptide structures, studying protein-protein interactions, and developing novel bioactive compounds.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new lead compounds with therapeutic potential.

Basic Information

Product Name	Z-Arg(Boc)2-OH·Cha
CAS No.	1899809-46-1
Molecular Formula	C30H48N6O8
Molecular Weight	620.74 g/mol
Synonyms	Nα-Z-Nω,Nω'-bis(tert-butoxycarbonyl)-L-arginine Cyclohexylamine Salt; Z-Arg(Boc)2-OH·C6H11NH2; Nα-Carbobenzoxy-Nω,Nω'-bis(tert-butoxycarbonyl)-L-arginine Cyclohexylammonium Salt; Z-L-Arg(Boc)2-OH·Cha; Boc-Protected Z-Arginine Cyclohexylamine Salt; Nα-Cbz-Nω,Nω'-di-Boc-L-arginine Cyclohexylamine Salt; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((bis(tert-butoxycarbonyl)amino)methyl)amino)pentanoic acid cyclohexylamine salt (related Fmoc variant context); Protected L-Arginine Derivative
EINECS	Contact for details

Quality Control

Our Z-Arg(Boc)2-OH·Cha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry for identity verification. We ensure compliance with relevant industry standards for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.