Description

Clopidogrel is a potent thienopyridine-class antiplatelet agent, widely recognized for its critical role in preventing thrombotic events. Its primary value lies in its ability to selectively and irreversibly inhibit the P2Y12 subtype of the ADP receptor on platelet surfaces, thereby preventing platelet activation and aggregation. This makes it an essential active pharmaceutical ingredient (API) for manufacturers of cardiovascular medications, particularly for patients with acute coronary syndrome, recent myocardial infarction, stroke, or established peripheral arterial disease.

Application

• Primary Active Pharmaceutical Ingredient (API) in antiplatelet tablets for cardiovascular disease prevention.
• Key intermediate in the synthesis of Clopidogrel bisulfate (Plavix®), a blockbuster medication.
• Research and development of novel anti-thrombotic drug formulations and combination therapies.
• Manufacturing of generic pharmaceutical products following patent expiry.
• Reference standard for analytical testing and quality control in pharmaceutical laboratories.
• Preclinical and clinical studies investigating new indications for platelet inhibition.

Basic Information

Product Name	Clopidogrel
CAS No.	1896709-41-3
Molecular Formula	C16H16ClNO2S
Molecular Weight	321.82 g/mol
Synonyms	Clopidogrel Base; Methyl (+)-(S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate; (S)-(+)-Clopidogrel; SR 25989; PCR 4099; Clopidogrelum; Iscover (base form)
EINECS	Contact for details

Quality Control

Our Clopidogrel is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. We provide comprehensive quality documentation, including Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. The material is produced in compliance with cGMP guidelines, and specifications can be aligned with major pharmacopoeial standards such as USP or EP upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place. Recommended storage temperature is between 15°C and 25°C. Ensure the storage area is well-ventilated and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Optical Rotation	+51.0° to +55.0° (c=1 in methanol)
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.