Description

(S)-4-Amino-6-((1-(3-Chloro-6-Phenylimidazo[1,2-B]Pyridazin-7-Yl)Ethyl)Amino)Pyrimidine-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound matters as a critical building block in the development of novel, targeted therapeutic agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization of novel drug candidates.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating specialized molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.
• Custom Synthesis & Contract Manufacturing: A critical component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services to the biopharma industry.

Basic Information

Product Name	(S)-4-Amino-6-((1-(3-Chloro-6-Phenylimidazo[1,2-B]Pyridazin-7-Yl)Ethyl)Amino)Pyrimidine-5-Carbonitrile
CAS No.	1894229-05-0
Molecular Formula	C19H15ClN8
Molecular Weight	390.83 g/mol
Synonyms	(S)-4-Amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl)amino)pyrimidine-5-carbonitrile; 1894229-05-0; (S)-4-Amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl)amino)-5-pyrimidinecarbonitrile; 4-Amino-6-[[(1S)-1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl]amino]-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 4-amino-6-[[(1S)-1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl]amino]-; AKOS026714031; F2198-1867; ZINC000257841601
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, chiral purity, and impurity profiles are available upon request. Our quality management system supports development under cGMP guidelines as required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Long-term storage under inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.