Description

4-(1,1-Difluoropropyl)- Benzenamine is a specialized aromatic amine derivative featuring a difluoropropyl substituent. This compound is a valuable fluorinated building block, prized for its ability to introduce unique physicochemical properties into target molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides, where the fluorinated moiety can enhance biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Polymer Modification: Employed to functionalize polymers, imparting specific characteristics like oil-repellency or altered dielectric properties.
• Cross-coupling Reactions: The aniline group makes it a suitable substrate for Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	4-(1,1-Difluoropropyl)- Benzenamine
CAS No.	1889542-64-6
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	4-(1,1-Difluoropropyl)aniline; 1-(4-Aminophenyl)-1,1-difluoropropane; Benzenamine, 4-(1,1-difluoropropyl)-; 4-(1,1-Difluoropropyl)phenylamine; p-(1,1-Difluoropropyl)aniline; 4-Amino-α,α-difluoropropylbenzene; 1889542-64-6
EINECS	Contact for details

Quality Control

Our 4-(1,1-Difluoropropyl)- Benzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent quality suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.