Description

2-[(6-Ethoxy-3,4-Dihydro-3-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Methyl]-Benzonitrile is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and agrochemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its unique pyrimidinedione core structure.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex molecules in medicinal chemistry and material science research.
• Process Development & Scale-Up: Serves as a standard for method development, optimization, and validation during the transition from laboratory to pilot and commercial-scale production.

Basic Information

Product Name	2-[(6-Ethoxy-3,4-Dihydro-3-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Methyl]-Benzonitrile
CAS No.	1883825-48-6
Molecular Formula	C₁₅H₁₅N₃O₃
Molecular Weight	285.30 g/mol
Synonyms	6-Ethoxy-3-methyl-2,4-dioxo-1-(2-cyanobenzyl)-1,2,3,4-tetrahydropyrimidine; 1-(2-Cyanobenzyl)-6-ethoxy-3-methylpyrimidine-2,4(1H,3H)-dione; 2-((6-Ethoxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile; 1883825-48-6; Ethoxy-methyl-dioxo-pyrimidinylmethyl-benzonitrile.
EINECS	Contact for details

Quality Control

Our 2-[(6-Ethoxy-3,4-Dihydro-3-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Methyl]-Benzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.