Description

n-(2-Bromo-5-Fluoro-Phenyl)-2,2,2-Trifluoro-Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated aromatic structure. This compound is essential for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturing facilities in the pharmaceutical and agrochemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and pesticides with enhanced efficacy.
• Chemical Synthesis: Used in organic synthesis for introducing the 2-bromo-5-fluoro-phenyl moiety into larger molecular frameworks.
• Material Science: Potential application in the research and development of specialty polymers and advanced materials.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process optimization for client projects.

Basic Information

Product Name	n-(2-Bromo-5-Fluoro-Phenyl)-2,2,2-Trifluoro-Acetamide
CAS No.	1882371-64-3
Molecular Formula	C8H4BrF4NO
Molecular Weight	286.03 g/mol
Synonyms	2-Bromo-5-fluoro-N-(trifluoroacetyl)aniline; 2',5'-Dibromo-2,2,2-trifluoroacetophenone (related precursor); N-(2-Bromo-5-fluorophenyl)-2,2,2-trifluoroacetamide; 2-Bromo-5-fluoro-trifluoroacetanilide; TFAA-Br-F-Ph-NH2 (abbrev.); 1882371-64-3; 2-Bromo-5-fluoroaniline trifluoroacetamide derivative
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-Fluoro-Phenyl)-2,2,2-Trifluoro-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.