Description

2-(Benzyloxy)-5-Fluorophenol is a high-purity fluorinated phenolic derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a protected phenol with a fluorine substituent, enabling precise modifications in complex chemical pathways. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine and phenolic functionalities into polymer chains, altering thermal stability, solubility, and surface properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorination reactions and creating complex molecular architectures.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that offer improved lightfastness and color properties.

Basic Information

Product Name	2-(Benzyloxy)-5-Fluorophenol
CAS No.	1881321-23-8
Molecular Formula	C₁₃H₁₁FO₂
Molecular Weight	218.22 g/mol
Synonyms	5-Fluoro-2-(phenylmethoxy)phenol; 2-Benzyloxy-5-fluorophenol; 5-Fluoro-2-benzyloxyphenol; 1-Benzyloxy-4-fluoro-2-hydroxybenzene; Phenol, 2-(benzyloxy)-5-fluoro-; 1881321-23-8; 2-(Benzyloxy)-5-fluorophenol
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-5-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring a reliable supply for critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.