Description

(3-Fluoro-2-Iodo-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, multi-functional chemical intermediate designed for advanced synthetic applications. This compound is valued for its unique halogenated aromatic structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly for creating fluorinated and iodinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine and iodine substituents can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its halogenated phenyl group for tuning material properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination due to the reactive iodine atom.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group is a standard amine protecting group, making this compound useful in peptide and complex molecule synthesis.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological testing.

Basic Information

Product Name	(3-Fluoro-2-Iodo-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1876444-72-2
Molecular Formula	C11H13FINO2
Molecular Weight	337.13 g/mol
Synonyms	tert-Butyl (3-fluoro-2-iodophenyl)carbamate; N-Boc-3-fluoro-2-iodoaniline; Boc-3-fluoro-2-iodoaniline; (3-Fluoro-2-iodophenyl)carbamic acid 1,1-dimethylethyl ester; 2-Iodo-3-fluoroaniline N-Boc derivative; N-(tert-Butoxycarbonyl)-3-fluoro-2-iodoaniline; Boc-Protected 3-fluoro-2-iodoaniline; t-Butyl N-(3-fluoro-2-iodophenyl)carbamate
EINECS	Contact for details

Quality Control

Our (3-Fluoro-2-Iodo-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, such as cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.